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Christina Applegate says she was misdiagnosed with multiple sclerosis

Christina Applegate, who first publicly announced a multiple sclerosis diagnosis in 2021, said on her podcast MeSsy that her doctor told her, "Congratulations, you don't have MS." She says she still has symptoms and plans to work with her doctors to find out what has been causing them since 2021.

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Why it matters

Christina Applegate has spoken publicly about multiple sclerosis since announcing her diagnosis in 2021. In a follow-up podcast episode, Cedars-Sinai neurologist Dr. Marwa Kaisey said her research found nearly one in five people told they have MS do not actually have it, because no single test confirms the disease.

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Published Wednesday, October 21, 2026. Spot an error? Email [email protected]. See our corrections log and standards.

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